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HMGN2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P05204 |
| Other Accession | P18437, P80272, NP_005508.1 |
| Reactivity | Human |
| Predicted | Pig, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 9393 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 3151 |
|---|---|
| Other Names | Non-histone chromosomal protein HMG-17, High mobility group nucleosome-binding domain-containing protein 2, HMGN2, HMG17 |
| Target/Specificity | This HMGN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HMGN2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | HMGN2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HMGN2 |
|---|---|
| Synonyms | HMG17 |
| Function | Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity). |
| Cellular Location | Nucleus. Cytoplasm. Note=Cytoplasmic enrichment upon phosphorylation |
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Provided below are standard protocols that you may find useful for product applications.
Background
HMGN2 binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in an unique chromatin conformation (By similarity).
References
Rattner, B.P., et al. Mol. Cell 34(5):620-626(2009)
Ueda, T., et al. Mol. Cell. Biol. 28(9):2872-2883(2008)
Cherukuri, S., et al. Mol. Biol. Cell 19(5):1816-1824(2008)
Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Porkka, K., et al. Proc. Natl. Acad. Sci. U.S.A. 99(11):7444-7449(2002)
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