PKD2L2 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | Q9NZM6 |
| Other Accession | NP_055201.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 73790 Da |
| Antigen Region | 193-219 aa |
| Gene ID | 27039 |
|---|---|
| Other Names | Polycystic kidney disease 2-like 2 protein, Polycystin-2L2, Polycystin-L2, PKD2L2 |
| Target/Specificity | This PKD2L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-219 amino acids from the Central region of human PKD2L2. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PKD2L2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PKD2L2 (HGNC:9012) |
|---|---|
| Synonyms | TRPP5 |
| Function | Exhibits a lower single conductance but no spontaneous channel activity (PubMed:16883570). May function as a regulator of calcium channels or a channel component involving Ca2(+) homeostasis (By similarity). |
| Cellular Location | Membrane {ECO:0000250|UniProtKB:Q9JLG4}; Multi- pass membrane protein |
| Tissue Location | Expressed only in testis (PubMed:10602361). Expressed also in brain and kidney (PubMed:10756092) |

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Provided below are standard protocols that you may find useful for product applications.
Background
PKD2L2 may function as a subunit of a cation channel and play a role in fertilization.
References
Li, Q., et al. FEBS Lett. 516 (1-3), 270-278 (2002) :
Stayner, C., et al. Trends Pharmacol. Sci. 22(11):543-546(2001)
Guo, L., et al. Genomics 64(3):241-251(2000)
Veldhuisen, B., et al. Eur. J. Hum. Genet. 7(8):860-872(1999)
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