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TOM1L2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q6ZVM7 |
| Other Accession | NP_001028723.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 55556 Da |
| Antigen Region | 474-500 aa |
| Gene ID | 146691 |
|---|---|
| Other Names | TOM1-like protein 2, Target of Myb-like protein 2, TOM1L2 |
| Target/Specificity | This TOM1L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-500 amino acids from the C-terminal region of human TOM1L2. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TOM1L2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TOM1L2 |
|---|---|
| Function | Acts as a MYO6/Myosin VI adapter protein that targets myosin VI to endocytic structures (PubMed:23023224). May also play a role in recruiting clathrin to endosomes (PubMed:16412388). May regulate growth factor-induced mitogenic signaling (PubMed:16479011). |
| Tissue Location | Ubiquitously expressed with higher expression in heart and skeletal muscle. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
TOM1L2 probable plays a role in protein transport. May regulate growth factor-induced mitogenic signaling.
References
Reynolds, C.A., et al. Hum. Mol. Genet. 19(10):2068-2078(2010)
Katoh, Y., et al. Biochem. Biophys. Res. Commun. 341(1):143-149(2006)
Franco, M., et al. Mol. Cell. Biol. 26(5):1932-1947(2006)
Zhang, Y., et al. Mol. Cell Proteomics 4(9):1240-1250(2005)
Zhang, Y., et al. Mol. Cell Proteomics 4(9):1240-1250(2005)
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