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IDAS Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - IDAS Antibody (N-term) AP18722a
    All lanes : Anti-IDAS Antibody (N-term) at 1:1000 dilution Lane 1: U-20S whole cell lysate Lane 2: T47D whole cell lysate Lane 3: Hela whole cell lysate Lane 4: Rat liver whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 42 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession D6RGH6
Other Accession G3N1S4, NP_001177716.1
Reactivity Human, Rat
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 41720 Da
Antigen Region 20-46 aa
Additional Information
Gene ID 345643
Other Names Multicilin, Multiciliate differentiation and DNA synthesis-associated cell cycle protein, Protein Idas, MCIDAS, IDAS, MCI, MCIN
Target/Specificity This IDAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-46 amino acids from the N-terminal region of human IDAS.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIDAS Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MCIDAS (HGNC:40050)
Synonyms IDAS, MCI, MCIN
Function Transcription regulator specifically required for multiciliate cell differentiation (PubMed:25048963). Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome- mediated acentriolar pathway (PubMed:25048963). Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1 (PubMed:21543332, PubMed:24064211).
Cellular Location Nucleus. Note=Excluded from the nucleolus
Research Areas
Citations (0)
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Background

Transcription regulator required for multiciliate cell differentiation. Acts by promoting transcription of genes required for multiciliate cell formation. Probably acts in a multiprotein complex By similarity. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Ref.1

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$ 365.00
$ 140.00
Cat# AP18722a
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