ACSM2A Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q08AH3 |
Other Accession | Q68CK6, NP_001010845.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 64223 Da |
Antigen Region | 41-67 aa |
Gene ID | 123876 |
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Other Names | Acyl-coenzyme A synthetase ACSM2A, mitochondrial, Acyl-CoA synthetase medium-chain family member 2A, Butyrate--CoA ligase 2A, Butyryl-coenzyme A synthetase 2A, Middle-chain acyl-CoA synthetase 2A, ACSM2A, ACSM2, MACS2 |
Target/Specificity | This ACSM2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-67 amino acids from the N-terminal region of human ACSM2A. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ACSM2A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ACSM2A |
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Synonyms | ACSM2, MACS2 |
Function | Catalyzes the activation of fatty acids by CoA to produce an acyl-CoA, the first step in fatty acid metabolism (By similarity). Capable of activating medium-chain fatty acids (e.g. butyric (C4) to decanoic (C10) acids), and certain carboxylate-containing xenobiotics, e.g. benzoate (By similarity). |
Cellular Location | Mitochondrion {ECO:0000250|UniProtKB:Q68CK6}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ACSM2A has medium-chain fatty acid:CoA ligase activity with broad substrate specificity (in vitro). Acts on acids from C(4) to C(11) and on the corresponding 3-hydroxy-and 2,3-or 3,4-unsaturated acids (in vitro) (By similarity).
References
Kochan, G., et al. J. Mol. Biol. 388(5):997-1008(2009)
Loftus, B.J., et al. Genomics 60(3):295-308(1999)
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