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IRX6 Antibody (Center)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - IRX6 Antibody (Center) AP18814c
    IRX6 Antibody (Center)(Cat. #AP18814c) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the IRX6 antibody detected the IRX6 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P78412
Other Accession NP_077311.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 48240 Da
Antigen Region 260-288 aa
Additional Information
Gene ID 79190
Other Names Iroquois-class homeodomain protein IRX-6, Homeodomain protein IRXB3, Iroquois homeobox protein 6, IRX6, IRX7, IRXB3
Target/Specificity This IRX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-288 amino acids from the Central region of human IRX6.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIRX6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IRX6
Synonyms IRX7, IRXB3
Function Transcription factor. Binds to the iroquois binding site (IBS) motif of target genes to regulate gene expression; functions as a transcriptional activator or repressor. Modulates expression of RCVRN, VSX1, BHLHE22/BHLHB5 and TACR3/Nk3r. Required downstream of retinal bipolar cell specification for the terminal differentiation of type 2, type 3a and possibly type 6 bipolar cells.
Cellular Location Nucleus.
Citations (0)
citation

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Background

The function of this protein remains unknown.

References

Ogura, K., et al. Cytogenet. Cell Genet. 92 (3-4), 320-325 (2001) :
Lewis, M.T., et al. Cell Tissue Res. 296(3):549-554(1999)

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$ 182.50
$ 70.00
Cat# AP18814c
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