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GANC Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8TET4 |
| Other Accession | NP_937784.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 104334 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 2595 |
|---|---|
| Other Names | Neutral alpha-glucosidase C, GANC |
| Target/Specificity | This GANC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GANC. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GANC Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GANC |
|---|---|
| Function | Has alpha-glucosidase activity. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes.
References
Oba-Shinjo, S.M., et al. J. Neurol. 256(11):1881-1890(2009)
Kawabata, Y., et al. FEBS Lett. 555(3):623-630(2003)
Dgany, O., et al. Am. J. Hum. Genet. 71(6):1467-1474(2002)
Hirschhorn, R., et al. Proc. Natl. Acad. Sci. U.S.A. 99(21):13642-13646(2002)
Usuki, F., et al. Muscle Nerve 11(4):365-371(1988)
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