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OLIG1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8TAK6 |
| Other Accession | NP_620450.1 |
| Reactivity | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 27905 Da |
| Antigen Region | 200-228 aa |
| Gene ID | 116448 |
|---|---|
| Other Names | Oligodendrocyte transcription factor 1, Oligo1, Class B basic helix-loop-helix protein 6, bHLHb6, Class E basic helix-loop-helix protein 21, bHLHe21, OLIG1, BHLHB6, BHLHE21 |
| Target/Specificity | This OLIG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the C-terminal region of human OLIG1. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | OLIG1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | OLIG1 |
|---|---|
| Synonyms | BHLHB6, BHLHE21 |
| Function | Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube (By similarity). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}. |
| Tissue Location | Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas is highly variable. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
OLIG1 promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube (By similarity).
References
Takei, H., et al. J. Neurooncol. 86(2):183-190(2008)
Ruf, N., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 144B (3), 365-366 (2007) :
Brena, R.M., et al. PLoS Med. 4 (3), E108 (2007) :
Stewart, S.E., et al. Arch. Gen. Psychiatry 64(2):209-214(2007)
Goris, A., et al. J. Neurol. Neurosurg. Psychiatr. 77(11):1296-1297(2006)
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