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GTPBP1 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GTPBP1 Antibody (C-term) AP18879b
    GTPBP1 Antibody (C-term)(Cat. #AP18879b) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the GTPBP1 antibody detected the GTPBP1 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O00178
Other Accession NP_004277.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 72454 Da
Antigen Region 578-608 aa
Additional Information
Gene ID 9567
Other Names GTP-binding protein 1, G-protein 1, GP-1, GP1, GTPBP1
Target/Specificity This GTPBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 578-608 amino acids from the C-terminal region of human GTPBP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGTPBP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GTPBP1
Function Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity (By similarity).
Cellular Location Cytoplasm.
Research Areas
Citations (0)
citation

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Background

This gene is upregulated by interferon-gamma and encodes a protein that is a member of the AGP11/GTPBP1 family of GTP-binding proteins. A structurally similar protein has been found in mouse, where disruption of the gene for that protein had no observable phenotype.

References

Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
Senju, S., et al. Mol. Cell. Biol. 20(17):6195-6200(2000)
Kudo, H., et al. Biochem. Biophys. Res. Commun. 272(2):456-465(2000)

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$ 182.50
$ 70.00
Cat# AP18879b
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