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RBMY1D Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P0C7P1 |
| Other Accession | Q15415, A6NEQ0, P0DJD4, A6NDE4, P0DJD3, NP_001006120.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 55775 Da |
| Antigen Region | 444-470 aa |
| Gene ID | 378949 |
|---|---|
| Other Names | RNA-binding motif protein, Y chromosome, family 1 member D, RBMY1D |
| Target/Specificity | This RBMY1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 444-470 amino acids from the C-terminal region of human RBMY1D. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RBMY1D Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RBMY1D |
|---|---|
| Function | RNA-binding protein which may be involved in spermatogenesis. Required for sperm development, possibly by participating in pre-mRNA splicing in the testis. |
| Cellular Location | Nucleus. |
| Tissue Location | Testis-specific. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked. [provided by RefSeq].
References
Tsuei, D.J., et al. Oncogene 23(34):5815-5822(2004)
Skaletsky, H., et al. Nature 423(6942):825-837(2003)
Chai, N.N., et al. Genomics 49(2):283-289(1998)
Prosser, J., et al. Mamm. Genome 7(11):835-842(1996)
Ma, K., et al. Cell 75(7):1287-1295(1993)
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