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TFG Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q92734 |
| Other Accession | NP_006061.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 43448 Da |
| Antigen Region | 184-212 aa |
| Gene ID | 10342 |
|---|---|
| Other Names | Protein TFG, TRK-fused gene protein, TFG |
| Target/Specificity | This TFG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-212 amino acids from the Central region of human TFG. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TFG Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TFG |
|---|---|
| Function | Plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules (PubMed:23479643, PubMed:27813252). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus (PubMed:21478858). |
| Cellular Location | Endoplasmic reticulum. Note=Localizes to endoplasmic reticulum exit site (ERES), also known as transitional endoplasmic reticulum (tER) (PubMed:21478858, PubMed:27813252). |
| Tissue Location | Ubiquitous. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene.
References
Miranda, C., et al. J. Cell. Physiol. 208(1):154-160(2006)
Roccato, E., et al. J. Biol. Chem. 280(5):3382-3389(2005)
Hisaoka, M., et al. Genes Chromosomes Cancer 40(4):325-328(2004)
Roccato, E., et al. Br. J. Cancer 87(6):645-653(2002)
Hernandez, L., et al. Am. J. Pathol. 160(4):1487-1494(2002)
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