KAL1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P23352 |
Other Accession | NP_000207.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 76112 Da |
Antigen Region | 166-194 aa |
Gene ID | 3730 |
---|---|
Other Names | Anosmin-1, Adhesion molecule-like X-linked, Kallmann syndrome protein, KAL1, ADMLX, KAL, KALIG1 |
Target/Specificity | This KAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the N-terminal region of human KAL1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | KAL1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ANOS1 (HGNC:6211) |
---|---|
Synonyms | ADMLX, KAL, KAL1, KALIG1 |
Function | Has a dual branch-promoting and guidance activity, which may play an important role in the patterning of mitral and tufted cell collaterals to the olfactory cortex (By similarity). Chemoattractant for fetal olfactory epithelial cells. |
Cellular Location | Cell membrane; Peripheral membrane protein. Secreted. Note=Proteolytic cleavage may release it from the cell surface into the extracellular space |
Tissue Location | Expressed in the cerebellum (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Mutations in this gene cause the X-linked Kallmann syndrome. The encoded protein is similar in sequence to proteins known to function in neural cell adhesion and axonal migration. In addition, this cell surface protein is N-glycosylated and may have anti-protease activity.
References
Dode, C., et al. Ann. Endocrinol. (Paris) 71(3):149-157(2010)
Tengara, S., et al. J. Dermatol. Sci. 58(1):64-71(2010)
Jian, B., et al. Cell Cycle 8(22):3770-3776(2009)
Tang, K.F., et al. Asian J. Androl. 11(6):711-715(2009)
Hu, Y., et al. J. Biol. Chem. 284(43):29905-29920(2009)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.