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TCN1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P20061 |
| Other Accession | NP_001053.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 48207 Da |
| Antigen Region | 406-433 aa |
| Gene ID | 6947 |
|---|---|
| Other Names | Transcobalamin-1, TC-1, Haptocorrin, HC, Protein R, Transcobalamin I, TC I, TCI, TCN1, TC1 |
| Target/Specificity | This TCN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 406-433 amino acids from the C-terminal region of human TCN1. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TCN1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TCN1 |
|---|---|
| Synonyms | TC1 |
| Function | Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach. |
| Cellular Location | Secreted. |
| Tissue Location | Produced by the salivary glands of the oral cavity, in response to ingestion of food. Major constituent of secondary granules in neutrophils. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells. [provided by RefSeq].
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Garrod, M.G., et al. Eur J Clin Nutr 64(5):503-509(2010)
Matteini, A.M., et al. J Nutr Health Aging 14(1):73-77(2010)
McGeachie, M., et al. Circulation 120(24):2448-2454(2009)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
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