SNAPC3 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q92966 |
Other Accession | Q4R6Y6, NP_001034786.1 |
Reactivity | Human |
Predicted | Monkey |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 46753 Da |
Antigen Region | 145-171 aa |
Gene ID | 6619 |
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Other Names | snRNA-activating protein complex subunit 3, SNAPc subunit 3, Proximal sequence element-binding transcription factor subunit beta, PSE-binding factor subunit beta, PTF subunit beta, Small nuclear RNA-activating complex polypeptide 3, snRNA-activating protein complex 50 kDa subunit, SNAPc 50 kDa subunit, SNAPC3, SNAP50 |
Target/Specificity | This SNAPC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-171 amino acids from the Central region of human SNAPC3. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SNAPC3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SNAPC3 |
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Synonyms | SNAP50 |
Function | Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box. |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
References
Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Jawdekar, G.W., et al. J. Biol. Chem. 281(41):31050-31060(2006)
Humphray, S.J., et al. Nature 429(6990):369-374(2004)
Hinkley, C.S., et al. J. Biol. Chem. 278(20):18649-18657(2003)
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