Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
TGM5 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O43548 |
| Other Accession | NP_004236.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 80778 Da |
| Antigen Region | 686-715 aa |
| Gene ID | 9333 |
|---|---|
| Other Names | Protein-glutamine gamma-glutamyltransferase 5, Transglutaminase X, TG(X), TGX, TGase X, Transglutaminase-5, TGase-5, TGM5, TGMX |
| Target/Specificity | This TGM5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 686-715 amino acids from the C-terminal region of human TGM5. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TGM5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TGM5 |
|---|---|
| Synonyms | TGMX |
| Function | Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes. |
| Cellular Location | Cytoplasm. Note=Associated with intermediate filaments |
| Tissue Location | Expressed in foreskin keratinocytes. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome.
References
Kiritsi, D., et al. J. Invest. Dermatol. 130(6):1741-1746(2010)
Kharfi, M., et al. J. Invest. Dermatol. 129(10):2512-2515(2009)
Broderick, P., et al. Cancer Res. 69(16):6633-6641(2009)
Pietroni, V., et al. J. Invest. Dermatol. 128(12):2760-2766(2008)
Cassidy, A.J., et al. Am. J. Hum. Genet. 77(6):909-917(2005)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
