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MFF Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9GZY8 |
| Other Accession | Q4KM98, Q6PCP5, Q3ZCD8, NP_064579.3 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 38465 Da |
| Antigen Region | 133-162 aa |
| Gene ID | 56947 |
|---|---|
| Other Names | Mitochondrial fission factor, MFF, C2orf33 |
| Target/Specificity | This MFF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-162 amino acids from the Central region of human MFF. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MFF Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MFF |
|---|---|
| Synonyms | C2orf33 |
| Function | Plays a role in mitochondrial and peroxisomal fission (PubMed:18353969, PubMed:23530241, PubMed:24196833). Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface (PubMed:23530241). May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles (By similarity). |
| Cellular Location | Mitochondrion outer membrane; Single-pass type IV membrane protein. Peroxisome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250|UniProtKB:Q4KM98} |
| Tissue Location | Highly expressed in heart, kidney, liver, brain, muscle, and stomach. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
MFF plays a role in mitochondrial and peroxisomal fission.
References
Gandre-Babbe, S., et al. Mol. Biol. Cell 19(6):2402-2412(2008)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
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$ 150.00
$ 385.00
Cat# AP19240c
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