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Mouse Gsta3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P30115 |
| Other Accession | NP_001070821.1 |
| Reactivity | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 25361 Da |
| Antigen Region | 183-211 aa |
| Gene ID | 14859 |
|---|---|
| Other Names | Glutathione S-transferase A3, GST class-alpha member 3, Glutathione S-transferase Ya3, Glutathione S-transferase Yc, Gsta3, Gstyc |
| Target/Specificity | This Mouse Gsta3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 183-211 amino acids from the C-terminal region of mouse Gsta3. |
| Dilution | WB~~1:4000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Mouse Gsta3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Gsta3 {ECO:0000312|MGI:MGI:95856} |
|---|---|
| Synonyms | Gstyc |
| Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Catalyzes isomerization reactions that contribute to the biosynthesis of steroid hormones. Efficiently catalyze obligatory double-bond isomerizations of delta(5)-androstene-3,17-dione and delta(5)-pregnene-3,20-dione, precursors to testosterone and progesterone, respectively (By similarity). Has a high catalytic activity for aflatoxin B1-8,9 epoxide (PubMed:1637297). |
| Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This GST has a high catalytic activity for aflatoxin B1-8,9 epoxide.
References
Ilic, Z., et al. Toxicol. Appl. Pharmacol. 242(3):241-246(2010)
Caruana, G., et al. Gene Expr. Patterns 6(8):807-825(2006)
Brown, A.C., et al. BMC Genet. 6, 12 (2005) :
Wang, Y., et al. Cancer Res. 64(5):1647-1654(2004)
Jowsey, I.R., et al. Biochem. Biophys. Res. Commun. 312(4):1226-1235(2003)
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