Mouse Plin3 Antibody(C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9DBG5 |
Other Accession | NP_080112.1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 47262 Da |
Antigen Region | 296-322 aa |
Gene ID | 66905 |
---|---|
Other Names | Perilipin-3, Cargo selection protein TIP47, Mannose-6-phosphate receptor-binding protein 1, Plin3, M6prbp1, Tip47 |
Target/Specificity | This Mouse Plin3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-322 amino acids from the C-terminal region of mouse Plin3. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Mouse Plin3 Antibody(C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Plin3 |
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Synonyms | M6prbp1, Tip47 {ECO:0000303|PubMed:15242 |
Function | Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets. Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network. |
Cellular Location | Lipid droplet {ECO:0000250|UniProtKB:O60664}. Endosome membrane {ECO:0000250|UniProtKB:O60664}; Peripheral membrane protein {ECO:0000250|UniProtKB:O60664}; Cytoplasmic side {ECO:0000250|UniProtKB:O60664}. Cytoplasm {ECO:0000250|UniProtKB:O60664}. Note=Membrane associated on endosomes Detected in the envelope and the core of lipid bodies and in lipid sails. {ECO:0000250|UniProtKB:O60664} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Plin3 is required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network (By similarity).
References
Hocsak, E., et al. FEBS Lett. 584(13):2953-2960(2010)
Lee, B., et al. Biochim. Biophys. Acta 1791(12):1173-1180(2009)
Skinner, J.R., et al. J. Biol. Chem. 284(45):30941-30948(2009)
Bell, M., et al. Diabetes 57(8):2037-2045(2008)
Straub, B.K., et al. Hepatology 47(6):1936-1946(2008)
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