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TSGA10 Antibody(N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - TSGA10 Antibody(N-term) AP19598a
    TSGA10 Antibody (N-term) (Cat. #AP19598a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TSGA10 antibody detected the TSGA10 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9BZW7
Other Accession NP_079520.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 81421 Da
Antigen Region 37-63 aa
Additional Information
Gene ID 80705
Other Names Testis-specific gene 10 protein, Testis development protein NYD-SP7, TSGA10, CEP4L
Target/Specificity This TSGA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-63 amino acids from the N-terminal region of human TSGA10.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTSGA10 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TSGA10
Synonyms CEP4L
Function Plays a role in spermatogenesis (PubMed:28905369). When overexpressed, prevents nuclear localization of HIF1A (By similarity).
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:Q9Z220}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=In mature spermatozoa, localizes to the centriole and midpiece (PubMed:28905369). The 27-kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail, while the 55-kDa peptide localizes to the midpiece (By similarity). Detected in the cytoplasm of almost all spermatogonial cells within the seminiferous tubules (By similarity). {ECO:0000250|UniProtKB:Q9Z220, ECO:0000269|PubMed:28905369}
Tissue Location Expressed in the testis, in spermatozoa (at protein level) (PubMed:11179690, PubMed:28905369). Expressed in actively dividing fetal tissues, including sternum, intestine, limb, kidney and stomach (PubMed:14585816).
Research Areas
Citations (0)
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Background

TSGA10 may play a role in the sperm tail fibrous sheath, a major sperm tail structure (By similarity).

References

Roghanian, A., et al. Cell. Immunol. 265(2):120-126(2010)
Reimand, K., et al. Int. Immunol. 20(1):39-44(2008)
Mobasheri, M.B., et al. Leuk. Res. 30(7):883-889(2006)
Tanaka, R., et al. Microbiol. Immunol. 48(4):339-345(2004)
Modarressi, M.H., et al. Gene 262 (1-2), 249-255 (2001) :

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$ 182.50
$ 70.00
Cat# AP19598a
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