TSGA10 Antibody(N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9BZW7 |
Other Accession | NP_079520.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 81421 Da |
Antigen Region | 37-63 aa |
Gene ID | 80705 |
---|---|
Other Names | Testis-specific gene 10 protein, Testis development protein NYD-SP7, TSGA10, CEP4L |
Target/Specificity | This TSGA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-63 amino acids from the N-terminal region of human TSGA10. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TSGA10 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TSGA10 |
---|---|
Synonyms | CEP4L |
Function | Plays a role in spermatogenesis (PubMed:28905369). When overexpressed, prevents nuclear localization of HIF1A (By similarity). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q9Z220}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=In mature spermatozoa, localizes to the centriole and midpiece (PubMed:28905369). The 27-kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail, while the 55-kDa peptide localizes to the midpiece (By similarity). Detected in the cytoplasm of almost all spermatogonial cells within the seminiferous tubules (By similarity). {ECO:0000250|UniProtKB:Q9Z220, ECO:0000269|PubMed:28905369} |
Tissue Location | Expressed in the testis, in spermatozoa (at protein level) (PubMed:11179690, PubMed:28905369). Expressed in actively dividing fetal tissues, including sternum, intestine, limb, kidney and stomach (PubMed:14585816). |
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Provided below are standard protocols that you may find useful for product applications.
Background
TSGA10 may play a role in the sperm tail fibrous sheath, a major sperm tail structure (By similarity).
References
Roghanian, A., et al. Cell. Immunol. 265(2):120-126(2010)
Reimand, K., et al. Int. Immunol. 20(1):39-44(2008)
Mobasheri, M.B., et al. Leuk. Res. 30(7):883-889(2006)
Tanaka, R., et al. Microbiol. Immunol. 48(4):339-345(2004)
Modarressi, M.H., et al. Gene 262 (1-2), 249-255 (2001) :
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