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HBZ Antibody(C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P02008 |
| Other Accession | NP_005323.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 15637 Da |
| Antigen Region | 95-123 aa |
| Gene ID | 3050 |
|---|---|
| Other Names | Hemoglobin subunit zeta, HBAZ, Hemoglobin zeta chain, Zeta-globin, HBZ, HBZ2 |
| Target/Specificity | This HBZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 95-123 amino acids from the C-terminal region of human HBZ. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | HBZ Antibody(C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HBZ |
|---|---|
| Synonyms | HBZ2 |
| Function | The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin. |
| Tissue Location | Detected in fetal erythrocytes (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Zeta-globin is an alpha-like hemoglobin. The zeta-globin polypeptide is synthesized in the yolk sac of the early embryo, while alpha-globin is produced throughout fetal and adult life. The zeta-globin gene is a member of the human alpha-globin gene cluster that includes five functional genes and two pseudogenes. The order of genes is: 5' - zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 -alpha-1 - theta1 - 3'.
References
Hivin, P., et al. J. Cell. Sci. 118 (PT 7), 1355-1362 (2005) :
He, Z., et al. Biochem. Biophys. Res. Commun. 325(4):1376-1382(2004)
Kidd, R.D., et al. Biochemistry 40(51):15669-15675(2001)
Lau, E.T., et al. Prenat. Diagn. 21(7):529-539(2001)
Daniels, R.J., et al. Hum. Mol. Genet. 10(4):339-352(2001)
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