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ZNF185 Antibody(N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O15231 |
| Other Accession | NP_001171579.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 73525 Da |
| Antigen Region | 155-183 aa |
| Gene ID | 7739 |
|---|---|
| Other Names | Zinc finger protein 185, LIM domain protein ZNF185, P1-A, ZNF185 |
| Target/Specificity | This ZNF185 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-183 amino acids from the N-terminal region of human ZNF185. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ZNF185 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ZNF185 |
|---|---|
| Function | May be involved in the regulation of cellular proliferation and/or differentiation. |
| Cellular Location | Cytoplasm, cytoskeleton. Cell junction, focal adhesion |
| Tissue Location | Expressed in placenta, pancreas and kidney. Also expressed in prostate, testis, ovary and blood |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a LIM-domain zinc finger protein. The LIM domain is composed of two contiguous zinc finger domains, separated by a two-amino acid residue hydrophobic linker. The LIM domain mediates protein:protein interactions. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
References
Zhang, J.S., et al. Oncogene 26(1):111-122(2007)
Medina, P.P., et al. Hum. Mol. Genet. 14(7):973-982(2005)
Vanaja, D.K., et al. Cancer Res. 63(14):3877-3882(2003)
Mallon, A.M., et al. Genome Res. 10(6):758-775(2000)
Heiss, N.S., et al. Genomics 43(3):329-338(1997)
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