MAN2C1 Antibody(N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | Q9NTJ4 |
| Other Accession | NP_006706.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 115835 Da |
| Antigen Region | 113-142 aa |
| Gene ID | 4123 |
|---|---|
| Other Names | Alpha-mannosidase 2C1, Alpha mannosidase 6A8B, Alpha-D-mannoside mannohydrolase, Mannosidase alpha class 2C member 1, MAN2C1, MANA, MANA1 |
| Target/Specificity | This MAN2C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-142 amino acids from the N-terminal region of human MAN2C1. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MAN2C1 Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MAN2C1 |
|---|---|
| Synonyms | MANA, MANA1 |
| Function | Cleaves alpha 1,2-, alpha 1,3-, and alpha 1,6-linked mannose residues on cytoplasmic free oligosaccharides generated by N- glycoprotein degradation pathways. |
| Cellular Location | Cytoplasm. |

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Provided below are standard protocols that you may find useful for product applications.
Background
MAN2C1 belongs to the glycosyl hydrolase 38 family.
References
Xiang, Z.G., et al. Transgenic Res. 19(1):67-75(2010)
Tian, Y., et al. Cancer Sci. 99(12):2428-2434(2008)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Qu, L., et al. Cell Res. 16(7):622-631(2006)
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