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PRSSL1 Antibody(C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IF, E |
|---|---|
| Primary Accession | Q6UWY2 |
| Other Accession | Q6IE59, Q14B24, NP_999875.1 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 30334 Da |
| Antigen Region | 225-254 aa |
| Gene ID | 400668 |
|---|---|
| Other Names | Serine protease 57, 3421-, Serine protease 1-like protein 1, PRSS57, PRSSL1 |
| Target/Specificity | This PRSSL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-254 amino acids from the C-terminal region of human PRSSL1. |
| Dilution | IF~~1:25 WB~~1:2000 FC~~1:25 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PRSSL1 Antibody(C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PRSS57 |
|---|---|
| Synonyms | PRSSL1 |
| Function | Serine protease that cleaves preferentially after Arg residues (PubMed:22474388, PubMed:23904161, PubMed:25156428). Can also cleave after citrulline (deimidated arginine) and methylarginine residues (PubMed:25156428). |
| Cellular Location | Cytoplasmic granule lumen. Secreted. Note=Stored in cytoplasmic granules and secreted as active enzyme in response to stimulation of neutrophils. |
| Tissue Location | Detected in peripheral blood neutrophil granulocytes, but not in other types of leukocytes. Detected in neutrophils and neutrophil precursors in bone marrow (at protein level) (PubMed:22474388, PubMed:23904161). Detected in myeloblasts and promyelocytes in bone marrow (PubMed:23904161) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein is unknown.
References
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Polikoff, D., et al. Cytogenet. Cell Genet. 79 (1-2), 147-148 (1997) :
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