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BCL9L Antibody(N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q86UU0 |
| Other Accession | NP_872363.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 157129 Da |
| Antigen Region | 147-176 aa |
| Gene ID | 283149 |
|---|---|
| Other Names | B-cell CLL/lymphoma 9-like protein, B-cell lymphoma 9-like protein, BCL9-like protein, Protein BCL9-2, BCL9L, DLNB11 |
| Target/Specificity | This BCL9L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 amino acids from the N-terminal region of human BCL9L. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | BCL9L Antibody(N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | BCL9L |
|---|---|
| Synonyms | DLNB11 |
| Function | Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1 (By similarity). |
| Cellular Location | Nucleus |
| Tissue Location | Expressed in breast, ductal and invasive ductal carcinomas of the breast, sporadic colorectal adenomas and carcinomas (at protein level). Expressed in fetal brain. Expressed in lung, amygdala, eye, prostate, pancreatic and prostate cancers, head and neck tumors and embryonal tumor. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1 (By similarity).
References
Miller, T.C., et al. J. Mol. Biol. 401(5):969-984(2010)
Fritzmann, J., et al. Gastroenterology 137(1):165-175(2009)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Sampietro, J., et al. Mol. Cell 24(2):293-300(2006)
Brembeck, F.H., et al. Genes Dev. 18(18):2225-2230(2004)
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