SH3BGRL Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | O75368 |
| Other Accession | Q4R7R5, Q58DU7, NP_003013.1 |
| Reactivity | Human |
| Predicted | Bovine, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 12774 Da |
| Antigen Region | 35-63 aa |
| Gene ID | 6451 |
|---|---|
| Other Names | SH3 domain-binding glutamic acid-rich-like protein, SH3BGRL |
| Target/Specificity | This SH3BGRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-63 amino acids from the Central region of human SH3BGRL. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SH3BGRL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SH3BGRL {ECO:0000303|PubMed:9642120} |
|---|---|
| Function | Appears to function as an adapter protein that bridges proteins together or proteins with mRNAs (PubMed:34331014). May function as a ubiquitin ligase-substrate adapter (PubMed:34331014, PubMed:34870550). Additionally, associates with translating cytoplasmic ribosomes and may promote the expression of specific mRNAs (PubMed:34331014, PubMed:34870550). |
| Cellular Location | Cytoplasm, cytosol. Cell membrane |
| Tissue Location | Ubiquitous.. |

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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein is unknown.
References
Naukkarinen, J., et al. PLoS Genet. 6 (6), E1000976 (2010) :
Majid, S.M., et al. Oncogene 25(5):756-768(2006)
Yin, L., et al. Proteins 61(1):213-216(2005)
Bruneel, A., et al. Proteomics 5(15):3876-3884(2005)
Ross, M.T., et al. Nature 434(7031):325-337(2005)
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