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GATAD2A Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q86YP4 |
| Other Accession | NP_060130.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 68063 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 54815 |
|---|---|
| Other Names | Transcriptional repressor p66-alpha, Hp66alpha, GATA zinc finger domain-containing protein 2A, GATAD2A |
| Target/Specificity | This GATAD2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GATAD2A. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | GATAD2A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | GATAD2A |
|---|---|
| Function | Transcriptional repressor (PubMed:12183469, PubMed:16415179). Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin (PubMed:16428440, PubMed:28977666). Enhances MBD2-mediated repression (PubMed:12183469, PubMed:16415179). Efficient repression requires the presence of GATAD2B (PubMed:16415179). |
| Cellular Location | Nucleus speckle. Nucleus. Chromosome. Note=Speckled nuclear localization requires both CR1 and CR2 regions (PubMed:16415179). Localizes to sites of DNA damage in a manner partially dependent on ZMYND8 (PubMed:27732854). |
| Tissue Location | Ubiquitous, both in fetal and adult tissues. |
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
GATAD2A is a transcriptional repressor.
References
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)
Brackertz, M., et al. Nucleic Acids Res. 34(2):397-406(2006)
Brackertz, M., et al. J. Biol. Chem. 277(43):40958-40966(2002)
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$ 182.50
$ 70.00
Cat# AP20258a
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