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PLOD2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- CITATIONS
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- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O00469 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 84686 Da |
| Antigen Region | 483-512 aa |
| Gene ID | 5352 |
|---|---|
| Other Names | Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2, Lysyl hydroxylase 2, LH2, PLOD2 |
| Target/Specificity | This PLOD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 483-512 amino acids from the C-terminal region of human PLOD2. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PLOD2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PLOD2 (HGNC:9082) |
|---|---|
| Function | Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. |
| Cellular Location | Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side |
| Tissue Location | Highly expressed in pancreas and muscle. Isoform 1 and isoform 2 are expressed in the majority of the examined cell types Isoform 2 is specifically expressed in skin, lung, dura and aorta |
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Provided below are standard protocols that you may find useful for product applications.
Background
Forms hydroxylysine residues in -Xaa-Lys-Gly-sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
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