|Application ||WB, E|
|Other Accession||Q8K114, Q4R5Z4, Q2KJA6|
|Predicted||Bovine, Monkey, Mouse|
|Calculated MW||73814 Da|
|Antigen Region||489-515 aa|
|Other Names||Integrator complex subunit 9, Int9, Protein related to CPSF subunits of 74 kDa, RC-74, INTS9, RC74|
|Target/Specificity||This INTS9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 489-515 amino acids from the C-terminal region of human INTS9.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||INTS9 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267).|
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Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.
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