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CDCA7L Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - CDCA7L Antibody (C-term) AP20468b
    CDCA7L Antibody (C-term) (Cat. #AP20468b) western blot analysis in 293,A2058,Ramos,U251,U937 cell line lysates (35ug/lane).This demonstrates the CDCA7L antibody detected the CDCA7L protein (arrow).
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession B3KTR5
Other Accession Q96GN5
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Antigen Region 290-317 aa
Additional Information
Other Names CDCA7L;HR1; JPO2; R1; Cell division cycle-associated 7-like protein; Cell division cycle-associated 7-like protein; Protein JPO2; Cell division cycle-associated 7-like protein; Transcription factor RAM2
Target/Specificity This CDCA7L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-317 amino acids from the C-terminal region of human CDCA7L.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCDCA7L Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Research Areas
Citations (0)
citation

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Background

Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

References

Huang A., et al. Cancer Res. 65:5607-5619(2005).
Chen K., et al. J. Biol. Chem. 280:11552-11559(2005).
Cathomen T., et al. Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.
Ota T., et al. Nat. Genet. 36:40-45(2004).
Scherer S.W., et al. Science 300:767-772(2003).

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$ 365.00
$ 140.00
Cat# AP20468b
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