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THY1 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 4
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | P04216 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 17935 Da |
| Antigen Region | 36-65 aa |
| Gene ID | 7070 |
|---|---|
| Other Names | Thy-1 membrane glycoprotein, CDw90, Thy-1 antigen, CD90, THY1 |
| Target/Specificity | This THY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human THY1. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | THY1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | THY1 |
|---|---|
| Function | May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. |
| Cellular Location | Cell membrane; Lipid-anchor, GPI- anchor |
Provided below are standard protocols that you may find useful for product applications.
Background
THY1 (CD90) antigen is a GPI linked glycoprotein member of the Immunoglobulin superfamily. It is expressed on murine T cells, thymocytes, neural cells, cells of granulocytic lineage, early hematopoietic progenitors, fibroblasts, neurons and Kupffer's cells. Thy1 may play a role in cell to cell or cell to ligand interactions during synaptogenesis and other events in the brain.
References
Koumas, L., et al., Am. J. Pathol. 163(4):1291-1300 (2003). Abeysinghe, H.R., et al., Cancer Genet. Cytogenet. 143(2):125-132 (2003). Saalbach, A., et al., Microvasc. Res. 64(1):86-93 (2002). Henniker, A.J., J. Biol. Regul. Homeost. Agents 15(4):392-393 (2001). Ye, Z., et al., Biochem. Biophys. Res. Commun. 275(1):223-227 (2000).
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