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POLR2H Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P52434 |
| Other Accession | Q923G2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 17143 Da |
| Gene ID | 5437 |
|---|---|
| Other Names | DNA-directed RNA polymerases I, II, and III subunit RPABC3, RNA polymerases I, II, and III subunit ABC3, DNA-directed RNA polymerase II subunit H, DNA-directed RNA polymerases I, II, and III 171 kDa polypeptide, RPB17, RPB8 homolog, hRPB8, POLR2H |
| Target/Specificity | This POLR2H antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 16-50 amino acids from the N-terminal region of human POLR2H. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | POLR2H Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | POLR2H (HGNC:9195) |
|---|---|
| Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. |
| Cellular Location | Nucleus {ECO:0000269|PubMed:33335104, ECO:0000269|PubMed:9852112, ECO:0000269|Ref.6}. Nucleus, nucleolus |
Provided below are standard protocols that you may find useful for product applications.
Background
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.
References
McKune K.,et al.Mol. Cell. Biol. 15:6895-6900(1995).
Shpakovski G.V.,et al.Mol. Cell. Biol. 15:4702-4710(1995).
Shpakovski G.V.,et al.Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
Bienvenut W.V.,et al.Submitted (AUG-2005) to UniProtKB.
Kershnar E.,et al.J. Biol. Chem. 273:34444-34453(1998).
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