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HUMAN-UMPS(Y37) Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P11172 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 52222 Da |
| Gene ID | 7372 |
|---|---|
| Other Names | Uridine 5'-monophosphate synthase, UMP synthase, Orotate phosphoribosyltransferase, OPRT, OPRTase, Orotidine 5'-phosphate decarboxylase, ODC, OMPdecase, UMPS |
| Target/Specificity | This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 30-70 amino acids from human. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | HUMAN-UMPS(Y37) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UMPS (HGNC:12563) |
|---|---|
| Function | Bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis, orotate phosphoribosyltransferase (OPRT), which converts orotate to orotidine-5'-monophosphate (OMP), and orotidine-5'-monophosphate decarboxylase (ODC), the terminal enzymatic reaction that decarboxylates OMP to uridine monophosphate (UMP). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Suttle D.P.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:1754-1758(1988).
Suchi M.,et al.Adv. Exp. Med. Biol. 253A:511-518(1989).
Suchi M.,et al.Am. J. Hum. Genet. 60:525-539(1997).
Griffith M.,et al.Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
Shichijo S.,et al.Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
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