TAAR5 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | O14804 |
Reactivity | Human |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 38242 Da |
Gene ID | 9038 |
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Other Names | Trace amine-associated receptor 5, TaR-5, Trace amine receptor 5, hTaar5, Putative neurotransmitter receptor, TAAR5, PNR |
Target/Specificity | This TAAR5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 236-269 amino acids from the C-terminal region of human TAAR5. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TAAR5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TAAR5 |
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Synonyms | PNR |
Function | Olfactory receptor specific for trimethylamine, a trace amine. Also activated at lower level by dimethylethylamine. Trimethylamine is a bacterial metabolite found in some animal odors, and to humans it is a repulsive odor associated with bad breath and spoiled food. This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase. |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Expressed almost exclusively in skeletal muscle and selected areas of the brain, such amygdala, hippocampus, caudate nucleus, thalamus and hypothalamus. Weak expression is also find in substantia nigra. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Olfactory receptor specific for trimethylamine, a trace amine. Also activated at lower level by dimethylethylamine. Trimethylamine is a bacterial metabolite found in some animal odors, and to humans it is a repulsive odor associated with bad breath and spoiled food. This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase.
References
Zeng Z.,et al.Biochem. Biophys. Res. Commun. 242:575-578(1998).
Lindemann L.,et al.Genomics 85:372-385(2005).
Staubert C.,et al.PLoS ONE 5:E11133-E11133(2010).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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