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Zebrafish waca Antibody (C-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q7ZUK7 |
| Reactivity | Zebrafish |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 60592 Da |
| Antigen Region | 487-519 aa |
| Gene ID | 323904 |
|---|---|
| Other Names | WW domain-containing adapter protein with coiled-coil, waca, wac |
| Target/Specificity | This Zebrafish waca antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 487-519 amino acids from zebrafish waca. |
| Dilution | WB~~1:2000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Zebrafish waca Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | waca |
|---|---|
| Synonyms | wac |
| Function | Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1). Positive regulator of amino acid starvation-induced autophagy. Positively regulates MTOR activity. May negatively regulate the ubiquitin proteasome pathway. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q9BTA9}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Acts as a linker between gene transcription and histone H2B monoubiquitination at 'Lys-120' (H2BK120ub1). Positive regulator of amino acid starvation-induced autophagy. May negatively regulate the ubiquitin proteasome pathway.
References
Song H.-D.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:16240-16245(2004).
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