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NRGN Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q92686 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 7618 Da |
| Gene ID | 4900 |
|---|---|
| Other Names | Neurogranin, Ng, RC3, NEUG(55-78), NRGN |
| Target/Specificity | This NRGN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 49-81 amino acids from the C-terminal region of human NRGN. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NRGN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NRGN |
|---|---|
| Function | Acts as a 'third messenger' substrate of protein kinase C- mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity). |
| Tissue Location | In the cerebral cortex, found in the cell bodies of neurons in layers II-VI, and in apical and basal dendrites of pyramidal neurons. Is not found in the dendrites in patients with Alzheimer disease. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Acts as a "third messenger" substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium (By similarity).
References
Mertsalov I.B.,et al.Bioorg. Khim. 22:366-369(1996).
Mertsalov I.B.,et al.Bioorg. Khim. 23:961-968(1997).
Martinez de Arrieta C.,et al.Genomics 41:243-249(1997).
Chang J.W.,et al.J. Neuropathol. Exp. Neurol. 56:1105-1118(1997).
Mertsalov I.B.,et al.Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
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