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NAGS Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8N159 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 58156 Da |
| Gene ID | 162417 |
|---|---|
| Other Names | N-acetylglutamate synthase, mitochondrial, Amino-acid acetyltransferase, N-acetylglutamate synthase long form, N-acetylglutamate synthase short form, N-acetylglutamate synthase conserved domain form, NAGS |
| Target/Specificity | This NAGS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 516-550 amino acids from the C-terminal region of human NAGS. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NAGS Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NAGS |
|---|---|
| Function | Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPS1) activity. |
| Cellular Location | Mitochondrion matrix |
| Tissue Location | Highly expressed in the adult liver, kidney and small intestine. Weakly expressed in the fetal liver, lung, pancreas, placenta, heart and brain tissue. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPSI) activity.
References
Haeberle J.,et al.Hum. Mutat. 21:593-597(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Caldovic L.,et al.Biochem. Biophys. Res. Commun. 299:581-586(2002).
Zhao G.,et al.PLoS ONE 8:E70369-E70369(2013).
Schmidt E.,et al.Biochim. Biophys. Acta 1740:54-59(2005).
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