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LSM2 Antibody (C-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q9Y333 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 10835 Da |
| Gene ID | 57819 |
|---|---|
| Other Names | U6 snRNA-associated Sm-like protein LSm2, Protein G7b, Small nuclear ribonuclear protein D homolog, snRNP core Sm-like protein Sm-x5, LSM2, C6orf28, G7B |
| Target/Specificity | This LSM2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 55-89 amino acids from human LSM2. |
| Dilution | WB~~1:2000 IHC-P~~1:25 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | LSM2 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LSM2 |
|---|---|
| Synonyms | C6orf28, G7B |
| Function | Plays a role in pre-mRNA splicing as component of the U4/U6- U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320). |
| Cellular Location | Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
Background
Binds specifically to the 3'-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing.
References
Achsel T.,et al.EMBO J. 18:5789-5802(1999).
Olavesen M.G.,et al.Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
Schmarda A.,et al.Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Xie T.,et al.Genome Res. 13:2621-2636(2003).
Shiina S.,et al.Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
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