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Ubiquilin3 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Ubiquilin3 Antibody (N-term) AP2177a
    Western blot analysis of anti-Ubiquilin3 Antibody (N-term) (Cat.#AP2177a) in K562 cell line lysates (35ug/lane). Ubiquilin3 (arrow) was detected using the purified Pab.
    detail
  • IHC-P - Ubiquilin3 Antibody (N-term) AP2177a
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9H347
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 70841 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 50613
Other Names Ubiquilin-3, UBQLN3
Target/Specificity This Ubiquilin3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Ubiquilin3.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsUbiquilin3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBQLN3
Tissue Location Testis specific..
Research Areas
Citations (0)
citation

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Background

Ubiquilin 3 shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and are thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. The gene is specifically expressed in the testis, and proposed to regulate cell-cycle progression during spermatogenesis.

References

Conklin, D., et al., Gene 249 (1-2), 91-98 (2000).

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$ 365.00
$ 140.00
Cat# AP2177a
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