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ZMAT3 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9HA38 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 32059 Da |
| Gene ID | 64393 |
|---|---|
| Other Names | Zinc finger matrin-type protein 3, Zinc finger protein WIG-1, p53-activated gene 608 protein, ZMAT3 {ECO:0000312|EMBL:AAH028961} |
| Target/Specificity | This ZMAT3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 170-204 amino acids from the Central region of human ZMAT3. |
| Dilution | WB~~1:8000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ZMAT3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ZMAT3 {ECO:0000312|EMBL:AAH02896.1} |
|---|---|
| Function | Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. |
| Cellular Location | Nucleus. Nucleus, nucleolus |
| Tissue Location | Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine. |
Provided below are standard protocols that you may find useful for product applications.
Background
Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus.
References
Varmeh-Ziaie S.,et al.Cancer Lett. 174:179-187(2001).
Hellborg F.,et al.Oncogene 20:5466-5474(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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