Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
PLAGL1 Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UM63 |
| Other Accession | Q2I689 |
| Reactivity | Human |
| Predicted | Pig |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 50819 Da |
| Gene ID | 5325 |
|---|---|
| Other Names | Zinc finger protein PLAGL1, Lost on transformation 1, LOT-1, Pleiomorphic adenoma-like protein 1, Tumor suppressor ZAC, PLAGL1, LOT1, ZAC |
| Target/Specificity | This PLAGL1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 112-146 amino acids from human PLAGL1. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PLAGL1 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PLAGL1 |
|---|---|
| Synonyms | LOT1, ZAC |
| Function | Acts as a transcriptional activator (PubMed:9722527). Involved in the transcriptional regulation of type 1 receptor for pituitary adenylate cyclase-activating polypeptide. |
| Cellular Location | Nucleus |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Shows weak transcriptional activatory activity. Transcriptional regulator of the type 1 receptor for pituitary adenylate cyclase-activating polypeptide.
References
Abdollahi A.,et al.Oncogene 14:1973-1979(1997).
Kas K.,et al.J. Biol. Chem. 273:23026-23032(1998).
Varrault A.,et al.Proc. Natl. Acad. Sci. U.S.A. 95:8835-8840(1998).
Bilanges B.,et al.Oncogene 20:1246-1253(2001).
Varrault A.,et al.Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
