FGFR1OP Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, E |
|---|---|
| Primary Accession | O95684 |
| Other Accession | Q4R7V3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 43065 Da |
| Antigen Region | 183-214 aa |
| Gene ID | 11116 |
|---|---|
| Other Names | FGFR1 oncogene partner, FGFR1OP, FOP |
| Target/Specificity | This FGFR1OP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 183-214 amino acids from the Central region of human FGFR1OP. |
| Dilution | WB~~1:1000-1:2000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FGFR1OP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CEP43 (HGNC:17012) |
|---|---|
| Synonyms | FGFR1OP, FOP |
| Function | Required for anchoring microtubules to the centrosomes (PubMed:16314388, PubMed:28659385). Required for ciliation (PubMed:28625565, PubMed:28659385). |
| Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Note=Associated with gamma-tubulin (PubMed:16314388). Localizes on both mother and daughter centrioles (PubMed:28428259, PubMed:28625565). Localizes to an axial position on the mother centriole (PubMed:28625565). Localizes to the distal end of the centriole partly on the subdistal appendage region (PubMed:28659385). |
| Tissue Location | Ubiquitous. Highly expressed in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis, and pancreas. |

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Provided below are standard protocols that you may find useful for product applications.
Background
Required for anchoring microtubules to the centrosomes.
References
Popovici C.,et al.Blood 93:1381-1389(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Andersen J.S.,et al.Nature 426:570-574(2003).
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