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NBAS Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | A2RRP1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 268571 Da |
| Antigen Region | 628-661 aa |
| Gene ID | 51594 |
|---|---|
| Other Names | Neuroblastoma-amplified sequence, Neuroblastoma-amplified gene protein, NBAS, NAG |
| Target/Specificity | This NBAS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 628-661 amino acids from the human NBAS. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NBAS Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NBAS (HGNC:15625) |
|---|---|
| Function | Involved in Golgi-to-endoplasmic reticulum (ER) retrograde transport; the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER (PubMed:19369418). Required for normal embryonic development (By similarity). May play a role in the nonsense-mediated decay pathway of mRNAs containing premature stop codons (By similarity). |
| Cellular Location | Cytoplasm. Endoplasmic reticulum. Endoplasmic reticulum membrane; Peripheral membrane protein |
| Tissue Location | Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small intestine and thymus. Well expressed in retinal ganglion cells, epidermal skin cells, and leukocytes. Up-regulated together with N-myc in some neuroblastoma cell lines. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Scott D.K.,et al.Gene 307:1-11(2003).
Hillier L.W.,et al.Nature 434:724-731(2005).
Wimmer K.,et al.Oncogene 18:233-238(1999).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Fruehwald M.C.,et al.J. Med. Genet. 37:501-509(2000).
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