USP32 Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q8NFA0 |
Reactivity | Human |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 181656 Da |
Gene ID | 84669 |
---|---|
Other Names | Ubiquitin carboxyl-terminal hydrolase 32, 3.4.19.12, Deubiquitinating enzyme 32, Renal carcinoma antigen NY-REN-60, Ubiquitin thioesterase 32, Ubiquitin-specific-processing protease 32, USP32, USP10 |
Target/Specificity | This USP32 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 438-470 amino acids from human USP32. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | USP32 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | USP32 |
---|---|
Synonyms | USP10 |
Function | Deubiquitinase that can remove conjugated ubiquitin from target proteins, such as RAB7A and LAMTOR1 (PubMed:36476874). Acts as a positive regulator of the mTORC1 signaling by mediating deubiquitination of LAMTOR1, thereby promoting the association between LAMTOR1 and the lysosomal V-ATPase complex and subsequent activation of the mTORC1 complex (PubMed:36476874). |
Cellular Location | Golgi apparatus membrane; Lipid-anchor |
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Provided below are standard protocols that you may find useful for product applications.
References
Paulding C.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:2507-2511(2003).
Sha J.H.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Zody M.C.,et al.Nature 440:1045-1049(2006).
Scanlan M.J.,et al.Int. J. Cancer 83:456-464(1999).
Olsen J.V.,et al.Cell 127:635-648(2006).
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