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SPTBN1 Antibody (C-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q62261 |
| Other Accession | Q01082 |
| Reactivity | Mouse |
| Predicted | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 274223 Da |
| Gene ID | 20742 |
|---|---|
| Other Names | Spectrin beta chain, non-erythrocytic 1, Beta-II spectrin, Fodrin beta chain, Spectrin, non-erythroid beta chain 1, SPTBN1, SPTB2 |
| Target/Specificity | This SPTBN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2063-2097 amino acids from mouse SPTBN1. |
| Dilution | WB~~1:2000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SPTBN1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Sptbn1 |
|---|---|
| Synonyms | Elf, Spnb-2, Spnb2, Sptb2 |
| Function | Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. Plays a critical role in central nervous system development and function. |
| Cellular Location | Cytoplasm, cytoskeleton. Endomembrane system. Cytoplasm, myofibril, sarcomere, M line. Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q01082}. Cell membrane {ECO:0000250|UniProtKB:Q01082}. Note=Colocalizes with ANK2 in a distinct intracellular compartment of neonatal cardiomyocytes |
| Tissue Location | Isoform 2 is present in brain, heart, kidney and liver (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
References
Hu R.J.,et al.J. Biol. Chem. 267:18715-18722(1992).
Chen Y.,et al.J. Mol. Neurosci. 17:59-70(2001).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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