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MAN1A2 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | O60476 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 73004 Da |
| Antigen Region | 342-373 aa |
| Gene ID | 10905 |
|---|---|
| Other Names | Mannosyl-oligosaccharide 1, 2-alpha-mannosidase IB, 3.2.1.113, Mannosidase alpha class 1A member 2, Processing alpha-1, 2-mannosidase IB, Alpha-1, 2-mannosidase IB, MAN1A2, MAN1B |
| Target/Specificity | This MAN1A2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 342-373 amino acids from the Central region of human MAN1A2. |
| Dilution | WB~~1:2000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | MAN1A2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MAN1A2 |
|---|---|
| Synonyms | MAN1B |
| Function | Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). |
| Cellular Location | Golgi apparatus membrane; Single-pass type II membrane protein |
| Tissue Location | Highest levels of expression in placenta and testis |
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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
References
Tremblay L.O.,et al.Glycobiology 8:585-595(1998).
Gregory S.G.,et al.Nature 441:315-321(2006).
Bienvenut W.V.,et al.Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
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