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NUP93 Antibody (C-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8N1F7 |
| Other Accession | Q5R822 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 93488 Da |
| Gene ID | 9688 |
|---|---|
| Other Names | Nuclear pore complex protein Nup93, 93 kDa nucleoporin, Nucleoporin Nup93, NUP93, KIAA0095 |
| Target/Specificity | This NUP93 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 752-782 amino acids from human NUP93. |
| Dilution | WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NUP93 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NUP93 |
|---|---|
| Synonyms | KIAA0095 |
| Function | Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance (PubMed:9348540). May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling (PubMed:26878725). |
| Cellular Location | Nucleus membrane {ECO:0000250|UniProtKB:Q66HC5}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q66HC5}. Nucleus, nuclear pore complex. Nucleus envelope Note=Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC.
References
Nagase T.,et al.DNA Res. 2:37-43(1995).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Martin J.,et al.Nature 432:988-994(2004).
Grandi P.,et al.Mol. Biol. Cell 8:2017-2038(1997).
Hase M.E.,et al.Mol. Biol. Cell 14:1923-1940(2003).
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