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SLC6A8 Antibody (N-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - SLC6A8 Antibody (N-Term) AP22082a
    Anti-SLC6A8 Antibody (N-Term) at 1:2000 dilution + mouse heart lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 71 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P48029
Other Accession O18875, Q8VBW1, P28570
Reactivity Mouse
Predicted Bovine, Rat
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 70523 Da
Additional Information
Gene ID 6535
Other Names Sodium- and chloride-dependent creatine transporter 1, CT1, Creatine transporter 1, Solute carrier family 6 member 8, SLC6A8
Target/Specificity This SLC6A8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 180-212 amino acids from human SLC6A8.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSLC6A8 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC6A8
Function Creatine:sodium symporter which mediates the uptake of creatine (PubMed:7953292, PubMed:7945388, PubMed:9882430, PubMed:17465020, PubMed:22644605, PubMed:25861866). Plays an important role in supplying creatine to the brain via the blood-brain barrier (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein
Tissue Location Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate
Research Areas
Citations (0)
citation

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Background

Required for the uptake of creatine in muscles and brain.

References

Nash S.R.,et al.Recept. Channels 2:165-174(1994).
Sora I.,et al.Biochem. Biophys. Res. Commun. 204:419-427(1994).
Sandoval N.,et al.Genomics 35:383-385(1996).
Barnwell L.F.,et al.Gene 159:287-288(1995).
Martinez-Munoz C.,et al.Gene 418:53-59(2008).

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$ 182.50
$ 70.00
Cat# AP22082a
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