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FABP4 Antibody (Y20)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P15090 |
| Other Accession | P70623, O97788, P04117, P48035 |
| Reactivity | Human, Mouse, Rat |
| Predicted | Bovine, Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 14719 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 2167 |
|---|---|
| Other Names | Fatty acid-binding protein, adipocyte, Adipocyte lipid-binding protein, ALBP, Adipocyte-type fatty acid-binding protein, A-FABP, AFABP, Fatty acid-binding protein 4, FABP4 |
| Target/Specificity | This FABP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from human FABP4. |
| Dilution | WB~~1:2000-1:8000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FABP4 Antibody (Y20) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FABP4 |
|---|---|
| Function | Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P04117}. Nucleus {ECO:0000250|UniProtKB:P04117}. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export. {ECO:0000250|UniProtKB:P04117} |
Provided below are standard protocols that you may find useful for product applications.
Background
FABP4 is a fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism.
References
Cabre,A., J. Lipid Res. 49 (8), 1746-1751 (2008)
Fasshauer,M., Am. J. Hypertens. 21 (5), 582-586 (2008)
Cabre,A., Clin. Chem. 54 (1), 181-187 (2008)
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