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COQ9 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | O75208 |
| Other Accession | Q68FT1, Q8K1Z0 |
| Reactivity | Human, Mouse |
| Predicted | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 35509 Da |
| Antigen Region | 156-184 aa |
| Gene ID | 57017 |
|---|---|
| Other Names | Ubiquinone biosynthesis protein COQ9, mitochondrial, COQ9, C16orf49 |
| Target/Specificity | This COQ9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the Central region of human COQ9. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | COQ9 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | COQ9 |
|---|---|
| Synonyms | C16orf49 |
| Function | Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Binds a phospholipid of at least 10 carbons in each acyl group. May be required to present its bound-lipid to COQ7. |
| Cellular Location | Mitochondrion {ECO:0000250|UniProtKB:Q8K1Z0}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Coenzyme Q10 (CoQ10), or ubiquinone, is a mobile lipophilic electron carrier critical for electron transfer by the mitochondrial inner membrane respiratory chain. COQ9 is 1 of several enzymes involved in biosynthesis of CoQ10 and likely functions in modification of the benzoquinone ring.
References
Duncan, A.J., et al. Am. J. Hum. Genet. 84(5):558-566(2009)
Loftus, B.J., et al. Genomics 60(3):295-308(1999)
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