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TPPP3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 3
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q9BW30 |
| Other Accession | Q5PPN5, Q9CRB6, Q3ZCC8 |
| Reactivity | Human, Mouse, Rat |
| Predicted | Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 18985 Da |
| Antigen Region | 117-146 aa |
| Gene ID | 51673 |
|---|---|
| Other Names | Tubulin polymerization-promoting protein family member 3, TPPP/p20, TPPP3 |
| Target/Specificity | This TPPP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 117-146 amino acids of human TPPP3. |
| Dilution | FC~~1:10~50 IHC-P~~1:50~100 WB~~1:2000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TPPP3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TPPP3 {ECO:0000303|PubMed:19633818, ECO:0000312|HGNC:HGNC:24162} |
|---|---|
| Function | Regulator of microtubule dynamic that has microtubule bundling activity (PubMed:17105200, PubMed:19633818). Required for embryo implantation; possibly by regulating beta-catenin (By similarity). Also required for decidualization via regulation of beta- catenin (PubMed:30667362). |
| Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton |
| Tissue Location | Expressed in endometrium during the mid-secretory phase (LH + 7) (at protein level). |
Research Areas
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
TPPP3 binds tubulin and has microtubule bundling activity. TPPP3 may play a role in cell proliferation and mitosis.
References
Zhou, W., et al. Mol. Cell. Biochem. 333 (1-2), 91-98 (2010) Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009) Vincze, O., et al. Biochemistry 45(46):13818-13826(2006)
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$ 150.00
$ 385.00
Cat# AP5004b
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